Library - JM Girardot

Peer-Reviewed Publications

1. Egly JM, Johnson BC, Stricker C, Mandel P, Kempf J, Pfleger N, Girardot JM. Newly phosphorylated proteins associated with cytoplasmic dRNA.FEBS Lett. 1972 May 1;22(2):181-184. (link)

2. Girardot JM, R Delaney and BC Johnson. Carboxylation, the completion step in prothrombin biosynthesis. Biochem Biophys Res Commun 59:1179-1203, 1974. (link)

3. Mack DO, ET Suen, JM Girardot, JA Miller, and BC Johnson. A soluble enzyme for vitamin K-dependent carboxylation. J Biol Chem 251:3269-3276, 1976. (link)

4. Girardot JM, DO Mack, RA Floyd, and BC Johnson. Evidence for vitamin K semiquinone as the functional form of vitamin K. Biochem Biophys Res Commun 70:655-662, 1976. (link)

5. Johnson BC, JM Girardot, ET Suen, DO Mack, and R Delaney. Biological role at molecular level of vitamin K. Symposium on Vitamin and Carrier Functions of Polyprenoids. World Review of Nutrition and Dietetics 31: 202-209, 1978. (link)

6. Mack, DO, M Wolfensberger, JM Girardot, JA Miller, and BC Johnson. The carboxylation activity of vitamin K analogs with substitution at the 2, 3 or 5 position. J Biol Chem 254:2656-2664, 1979. (link)

7. Girardot JM and BC Johnson. A new detergent for solubilization of vitamin K dependent carboxylation system from liver microsomes: Comparison with Triton X-100. Anal Biochem 121:315-320, 1982. (link)

8. Girardot JM. Vitamin K-dependent carboxylase: Partial purification and properties of the enzyme-substrate complex. J Biol Chem, 257:15008-15011, 1982. (link)

9. Girardot JM, J Kempf, and DMF Cooper. Role of calmodulin in the effect of guanyl nucleotides on rat hippocampal adenylate cyclase: Involvement of adenosine and opiates. J Neurochem 41:848-859, 1983. (link)

10. Kanabus-Kaminska JM and JM Girardot. Inhibition of vitamin K-dependent carboxylase by metal ions and metal complexes: A reassessment. Arch Biochem Biophys 228, 646-652, 1984. (link) (link)

11. Zeiner AR, Girardot JM, Jones-Saumty D, Nichols N. Prevalence of ALDH isoenzymes among American Indians in Oklahoma Arukoru Kenkyuto Yakubutsu Ison. 1985 Dec;20(4):359-66. (link)

12. Johnson BC and JM Girardot. Requirement of antichaotropic reagents for activity of reduced vitamin K quinone-dependent enzyme. Chemica Scripta 27A:175-186, 1987.

13. Girardot JM, JP Gott, RA Guyton, and FJ Schoen. A novel technology inhibits calcification of bioprosthetic heart valves: A sheep pilot study. Trans Soc Biomaterials 14:60, 1991.

14. Girardot MN, JM Girardot and FJ Schoen. Alpha amino oleic acid, a new compound, prevents calcification of bioprosthetic heart valves. Trans Soc Biomaterials 14:114, 1991.

15. Gott JP, Pan-Chih, LMA Dorsey, JL Jay, GK Jett, FJ Schoen, RA Guyton, and JM Girardot. Calcification of porcine valves: A successful new method of antimineralization. Ann Thorac Surg 53:207-216, 1992. (link) (link)

16. Girardot MN, JM Girardot, FJ Schoen, JP Gott, RA Guyton, DJ Myers, and F Dixon-Helfer. Development of the AOA process: an antimineralization treatment for bioprosthetic heart valves. Trans Soc Biomaterials 19:266, 1993.

17. Girardot MN and JM Girardot. Analytical determination of composition within thick tissue: The aortic wall of the AOA-treated heart valve as an example. Trans Soc Biomaterials 20:223, 1994.

18. Girardot MN, WM Torrianni and JM Girardot. Effect of AOA on glutaraldehyde-fixed bioprosthetic heart valve cusps and walls: Binding and calcification studies. Int J Artificial Organs 17:76-82, 1994. (link)

19. MN Girardot, M Torrianni, D Dillehay, and JM Girardot. Role of glutaraldehyde in calcification of porcine heart valves: Comparing cusp and wall. J Biomed Mater Research, 29:793-801, 1995. (link - abstract)(link - article)

20. Girardot JM and MN Girardot. Amide cross-linking: An alternative to glutaraldehyde fixation. J Heart Valve Disease 5:518-525, 1996. (link)

21. Gott JP, MN Girardot, JM Girardot, JD Hall, J Whitlark, WS Horsley, LMA Dorsey, RJ Levy, W Chen, FJ Shoen, and RJ Guyton. Refinement of the alpha-aminooleic acid bioprosthetic valve anticalcification technique. Ann Thorac Surg 64,50-58,1997. (link)

Book Chapters

1. Johnson BC, DO Mack, R Delaney, MR Wolfensberger, C Esmon, JA Price, E Suen, and JM Girardot. Vitamin K analogs in the study of vitamin K-dependent carboxylation. In: Vitamin K Metabolism and Vitamin K-dependent Proteins, JW Suttie, Ed, University Park Press, Baltimore, Maryland, pp 455-466, 1980.

2. Girardot JM and JM Kanabus-Kaminska. Vitamin K-dependent carboxylase from rat liver. In: Posttranslational Covalent Modification of Proteins, BC Johnson, Ed, Academic Press, NY, pp 205-213, 1983.

3. Girardot MN, JM Girardot and MW Torrianni. Alpha-aminooleic acid anticalcification effect of glutaraldehyde-fixed heart valves: Shelf-life studies. In: New Horizons and the Future of Heart Valve Bioprostheses, First Edition, S Gabbay and RWM Frater, Eds, Silent Partners, Austin, TX, pp 41-51, 1994.

4. Girardot JM, MN Girardot, JP Gott, C Eberhardt, DA Myers, and MW Torrianni. Preclinical testing for antimineralization treatments of heart valve bioprostheses. In: Encyclopedic Handbook of Biomaterials and Applications, Part B: Applications, DL Wise et al, Eds, Marcel Decker, New York, Vol 2, pp 1189-1230, 1995.

5. Girardot MN, JM Anderson, M MacDonald, I Duarte, WM Brown, and JM Girardot. Biocompatility and calcification cvaluation of porcine aortic valves cross-linked with Ultifix®. In: Advances in Anticalcific and Antidegenerative Treatment of Heart Valve Bioprostheses, S Gabbay and DJ Wheatley, eds., Silent Partners, Austin TX, pp 93-104, 1997.

6. Gott JP, MN Girardot, JM Girardot, and RA Guyton. Preclinical evaluation of improved treatment with alpha aminooleic acid confirming antimineralization efficacy and preservation of tissue integrity. In: Advances in Anticalcific and Antidegenerative Treatment of Heart Valve Bioprostheses, S Gabbay and DJ Wheatley, eds., Silent Partners, Austin TX, pp1 57-166, 1997.


1. Girardot, JM. Prevention of prosthesis calcification. U.S. Patent 4,976,733, December 11, 1990. (link)

2. Girardot, JM and Girardot, MN. Method for fixation of biological tissue. U.S. Patent 5,447,536, September 5, 1995. (link)

3. Girardot, JM and Girardot, MN. Process for fixation of calcification-resistant biological tissue. U.S. Patent 5,733,339, March 31, 1998. (link)

4. Girardot, JM and Girardot, MN. Method of sterilization. U.S. Patent 5,911,951, June 15, 1999. (link)

5. Girardot, JM and Girardot, MN. Method of sterilization. U.S. Patent 6,506,339, January 14, 2003. (link)

6. Girardot, JM and Girardot, MN. Sterilization. U.S. Patent 6,521,179, February 18, 2003. (link)

7. Girardot, JM and Girardot, MN. Calcification resistant fixation. U.S. Patent 7,479,164, January 20, 2009. (link)

8. Girardot, JM and Girardot, MN. Variably crosslinked tissue. U.S. Patent 7,918,899, April 5, 2011. (link)